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Neuroimaging APT CEST V.1.0 imaging solution
MRI

Mapping peptides and proteins to detect molecular changes in the brain

Advanced post-processing application for Chemical Exchange Saturation Transfer (CEST) MRI images dedicated to the weighted data applied to the amide proton transfer.

Use dedicated to research

Alignment with anatomical sequences and placement of ROI and VOI
Alignment of calculated maps with structural maps to extract accurate key results from VOI and ROI.

Different palettes and displays available for APTw maps
Adaptive display of maps for customized analysis and to highlight any potentially anomalous areas.

Additional maps available
A wide panel of calculated maps allowing for procuring various parameters to monitor and analyze.

APT-CEST booklet Download

APT CEST Brain: Glioma
Multiparametric MRI in brain tumours is an invaluable methodology for obtaining in-depth information for the structural and functional tissue features guiding the differential diagnosis and assisting the tumour staging. Each MRI parametric maps provides crucial information for the different histomolecular tumour substrates, whereas the ‘tier-like’ interpretation of the combined structural-functional outputs helps the radiologist to reach an accurate diagnosis.
Download
APT-CEST imaging in the distinction between radionecrosis & tumor recurrence in brain metastasis
This case report shows the potential added value of Amide Proton Transfer (APT) contrast in the discrimination between radio-induced toxicity lesions and tumor progression in brain metastatic disease.
Download

The APT CEST solution

Present in

+ 1

clinical and research centers

Needs on average

0 s

for the post-processing of our maps

Is mentioned in

+ 0

reviews and one conference article

Overview of the main functions		APT CEST
B0 calculated map (with WASAB1 or Z-Spectra or an external map)
rB1 calculated map (with WASAB1)
B0 correction
B1 correction
Spatial noise reduction
Fluid suppression (with “spillover” effect correction)
APTw calculation at different frequency offset ranges
Alignment with the structural maps
PCA noise reduction
Motion correction