JFR 2026

Moderated by Prof. Jean-Pierre Pruvo, this session brings together two neuroradiologists practicing in France and in the United States, Dr. Charles Mellerio and Prof. Lotfi Hacein-Bey, around a simple question: today, in MRI, what do we really know how to measure, and what actually helps in making decisions?

Three parts to answer it. First, the tumor. A case managed “the old-fashioned way,” from the first CT scan all the way to the operating room, serves as the starting point. Each step is then revisited with what quantification changes: perfusion for neoangiogenesis, fMRI before surgery, volumetry for follow-up, and APT-CEST when a decision must be made between pseudoprogression, radionecrosis and recurrence. Next, vascular and neurodegenerative disease, from what is already in place, with emergency stroke triage and microbleeds on SWI, to what is coming: cerebral oxygenation (OEF, CMRO2) and REACT, which adds information on receptors to fMRI and opens avenues as far as psychiatry. Finally, a before/after review of both parts, to sort out what can be used right now in one’s department and what still belongs to research.

⇒ A format anchored in concrete cases, two perspectives from the field, and a clear idea of what quantification can change in practice.

Symposium in French